Blog from September, 2015

A Hydroquinone Alternative

DATE : 2015-09-29

 

NuGene International, Inc. a developer, manufacturer and marketer of skin and hair care lines utilizing adipose derived human stem cells and stem cell media, was featured in a study and presentation by Dr. Dendy Engelman, a NuGene advisory board member and director of dermatological surgery at New York Medical College. According to the Global Industry Analysts, Inc. (GIA), the global market for skin lighteners is projected to reach $23 billion by 2020, driven by the desire among both women and men to have even-toned skin. With a proven alternative to hydroquinone, NuGene has a significant opportunity to impact this expanding market, according said Dr. Saeed Kharazmi, chairman and co-founder of NuGene.

 

Engelman's presentation titled, Potent Human Adipose Derived Stem Cell Treatments Revolutionizing Topical Anti-Aging Therapy, described a limited study performed to assess the efficacy of NuGene's Light and Bright Gel in improving the appearance of skin pigmentation. In the study, blinded investigators observed an improvement in skin pigmentation appearance with all patients where:

  • 33% of patients experienced a 50% improvement in skin appearance
  • 56% of patients experienced a 75% improvement in skin appearance

 

The subjects of the study were females between the ages of 30 to 60 years old, with hyperpigmentation on the face with moderate severity. The products used in the study featured NuGene's unique stem cell based technology employing a high concentration of bioactive molecules from stem cell culture media derived from human adipose stem cells.

 

In the study, the information was collected by an independent investigator who was provided with photographic evidence showing before and after images of the participants and concluded that there was significant improvement in the lack of the appearance of aging. Images of participants before and after the use of the product can be viewed here.

 

"NuGene's Light and Bright Gel provides an innovative approach to skin and hair rejuvenation. Clinical findings from topical application of NuGene's product yielded results, in my opinion, previously only attainable by in-office procedures. I have been overwhelmed by the efficacy of this product and am thrilled to offer this product line to my patients," remarked Engelman.

 

"Dr. Engelman presented NuGene's non-hydroquinone based solution for hyperpigmentation aesthetics to some of the world's top dermatologists and aestheticians. NuGene has a significant opportunity to impact this expanding market," said Dr. Saeed Kharazmi, Chairman and co-founder of NuGene. Hydroquinone, a common component of bleaching creams, has already been banned in Japan, the European Union, and Australia due to potential cancer concerns.

 

SOURCE Happi

 

Butadiene production in the second quarter of 2015 was reported to be approximately 346,000t -  an increase from the first quarter and better than the quarterly average in 2014. Butadiene output from US crackers increased due to a modest rise in propane, butane and naphtha cracking. The shift in cracker feedstock preference was somewhat seasonal as propane and butane demand drops and prices decline in the spring months; however, higher production from shale gas and the collapse of energy values over the past year have also added to the lower cost of LPG's. In fact, butane prices today are at the lowest levels since mid-2012.

 

Source: Dewitt August 19 2015

 

DATE : 2015-09-16

 

The global acrylic acid market is forecast to reach US$18.8 bln by 2020 from US$11 bln in 2013, registering a CAGR of 7.6% during the forecast period of 2014 - 2020. The global consumption of acrylic acid would reach 8,169 kilo tons by 2020, as per Allied Market Research. Acrylic acid as precursor for various chemicals processes and as an intermediary for industrial processes such as surface coating, paper treatment, plastic additives, and textiles; has witnessed a surge in demand over past few years. The factors fueling the demand of acrylic acid market are growth in demand for superabsorbent polymers, growing usage of acrylic-based products in emerging economies and further development in the industries such as adhesives and sealants. Stringent government regulations pertaining to the environmental safety & human health and volatile prices of the raw materials are restricting the growth of the market globally.
Production of acrylic acid largely depends on fossil fuel resources; therefore, due to the rising price of crude oil globally, manufacturers are now focusing on developing and commercializing renewable acrylic acid. Recently, BASF, Novozymes, and Cargill jointly developed 3-hydroxypropionic acid (3-HP), a raw material for bio-based acrylic acid, in pilot scale. On the other hand, OPX Biotechnologies is aiming to commercialize bio acrylic acid by 2017 with its partner Dow Chemicals. Metabolix has successfully developed bio-based acrylic acid using FAST (fast-acting, selective thermolysis) technique in laboratory setting. Such and other developments will provide a platform for the future growth of acrylic acid globally due to its cost advantage, efficiency and its eco-friendly product outcomes.
Among acrylic esters, acrylic polymers and other derivatives; acrylic esters segment leads the global market both in terms of volume as it is widely used as raw materials for producing adhesives, water-based paints, synthetic rubbers and synthetic resins. Acrylic polymers is the fastest growing segment in the derivative types market due to its broad spectrum of applications in industries such as surface coatings, surfactants, diapers and cosmetics. Diapers segment is the largest consumer of acrylic acid in form of superabsorbent polymers and accounts for over 1/4th of the market revenue. Surface coating, adhesives & sealants and plastic additive are other top three major consumers of acrylic acid. Water treatment, textiles, and surfactants are among other end use segments. Surfactants would be fastest growing end use segment during the forecast period.
Geographically, Asia Pacific holds the largest share of revenue and would continue to dominate the global acrylic acid market through 2020. LAMEA is projected to hold fastest growth potential, growing at a CAGR of 9.3% during the forecast period. North America and Europe will have steady growth during the forecast period due to saturation in end use segments.

 

SOURCE Plastemart

I took the opportunity of this announcement of LG to rephrase the estimated growth of acrylic acid and SAP :

 

August 19, 2015: LG Chem says it has completed expansion work on its acrylic acid and a super absorbent polymer (SAP) plants at Yeosu, South Korea.

 

The company announced the 320 billion South Korean won ($269.7 million) expansion at the end of 2013. The project raised acrylic acidcapacity from 350 kt/a to 510 kt/a and added 80 kt/a SAP capacity, bringing the total at Yeosu to 360 kt/a.

 

LG Chem, following the hike, ranks as the world’s fifth largest in acrylic acid and fourth-largest in SAP in capacity terms. The company forecasts an additional won300 billion in sales following the new investment.

 

LG Chem is planning to increase its acrylic acid and SAP-related salesby 600 billion won (US$504 million) or so to at least 1.7 trillion won (US$1.4 billion) by 2020. LG Chem forecasts the market for acrylic acid to grow from 4.9 mt/a last year to 6.7 mt/a by 2020, while that of SAP is estimated to increase from 2.3 mt/a to 3.4 mt/a during the next five years.

 

 

LG Chem had delved into the materials since the 1990s and came up with its own acrylic acid catalyst and production techniques in 2004 for the first time in Korea. At present, only a handful of companies such as BASF, Dow, NSCL, and Mitsubishi have their own processing techniques in this industry.

 

Last year, BASF and Sinopec have inaugurated two new plants for acrylic acid (160 kt/a) and SAP (60 kt/a) at their Verbund site, BASF-YPC Co., Ltd. in Nanjing, China to further strengthen the C3 (propylene) value chain. (see: BASF and Sinopec inaugurate acrylic acid and SAP plants in Nanjing, China)

 

In December 2013, Mitsubishi Chemical and SK Global Chemical, through a strategic alliance with, planned to build an acrylic acid plant at Ulsan, Korea by 2016. (see: SK Global to build acrylic acid and derivatives plants in Korea as part of portfolio diversification) The plant will be designed to produce 160 kt/a acrylic acid. SK is considering construction of a SAP plant using acrylic acid from the new plant.

 

Source: Solvya blog competitive intelligence blog from “Chemweek” and “BusinessKorea”

Syngenta has announced that its succinate dehydrogenase inhibitor (SDHI) fungicide Solatenol (benzovindiflupyr) has received registration from Canada’s Pest Management Regulatory Agency (PMRA).

Benzovindiflupyr is reported to have a broad spectrum of activity against a number of foliar and soil dwelling pathogens, including rusts, Septoria spp., apple scab, powdery mildew, and Rhizoctoniaspp. In addition, the product reportedly benefits from efficacy at lower use rates compared to other SDHI fungicides, flexible application timing, tank-mix compatibility and the potential for use in resistance management strategies.

The active ingredient is expected to be available in Canada from the spring of 2016 in three new products: Aprovia, a solo formulation for use on pome fruits and blueberries; Elatus, with azoxystrobin for use on pulse crops such as lentils, chickpeas and field peas; and Trivapro with azoxystrobin and propiconazole for use on maize, soybeans and wheat.

 

Source:

PhillipsMcDougall

AgreWorld Daily Note - 02 September 2015

 

DATE : 2015-09-01

 

Evonik Industries has commenced new manufacturing plants for C4-based products in the Marl Chemical Park, Germany. This expansion of production in Marl is part of a capacity expansion throughout Europe for C4-based products, in which Evonik has invested a three-digit million Euro amount in total.

At the heart of the new plants at Evonik's largest site is the widely visible 90-meter column, the highest within the specialty chemicals company. This is a symbol of a new technology that, for the first time anywhere in the world, utilises special material streams from refineries for production of C4 chemicals. These streams are supplied by the neighbouring BP refinery in Gelsenkirchen.

Evonik is one of the leading global suppliers of C4-based products such as butadiene, MTBE, isobutene, 1-butene, and INA (isononanol) as well as 2-PH (2-propylheptanol) and DINP (diisononyl phthalate).

Klaus Engel, chairman of the executive board of Evonik, said, "With the expansion of our C4 capacitieswe are sustainably strengthening our market position. What's more, the new technology for raw material supply for the Marl plant and our excellent collaboration with BP demonstrate yet again the innovative strength of companies in the Ruhr district and their readiness to collaborate. We are confident, therefore, that there will continue to be a strong industrial base in the region."

In addition to the expansion in Marl, Evonik has also invested in the C4 activities in Antwerp, Belgium, where the plants in question went on stream in the second quarter of 2015. The new production facilities have resulted in capacity expansion for the plasticiser alcohol isononanol in Marl, butadiene in Antwerp, and the fuel additive MTBE in both Marl and Antwerp.

Johann-Caspar Gammelin, chairman of the Board of Management of Evonik Performance Materials GmbH, says: "Our investments are supporting the growth plans of our customers in Europe and worldwide. Market analyses show that global demand for these products is growing by up to 5 percent annually."

The Marl plant also marks a technological milestone for Evonik. Thanks to an entirely new process worldwide, FCC-C4 material streams can be used for production of a wider range of chemicals. "The new technology significantly expands our raw-material base. It gives us access to raw-material streams that have so far not been used for downstream chemical processing," explained Gammelin. The steam or naphtha cracker has so far been the major source for extraction of basic petrochemicals. However, there are significantly more FCC crackers than steam crackers worldwide.

FCC stands for fluid catalytic cracking. With the help of this process, refineries transform heavy crude oil components in fuel components. Fluid catalytic cracking produces a C4 material stream that, besides the components that can be used for chemical processing (olefins), contains further accompanying substances. The industry has therefore so far not used this FCCC4 material stream.

By developing its own new technologies and combining these with others procured externally, Evonik has now succeeded in utilising this material stream from the refinery. The main challenge here lay in separating any unwanted accompanying substances from the FCC-C4 stream. The new technology incorporates various chemical reactions and absorption techniques that allow an efficient yet flexible process. The 90-meter column removes the saturated compounds (butanes), which are of less interest toEvonik, from the FCC-C4 material stream, so that the more valuable unsaturated C4 compounds (butenes) can be further processed to specialty chemicals.

Innovation and collaboration in the Ruhr district Evonik draws the FCC-C4 material stream by pipeline from the refinery in Gelsenkirchen, about 15 km from the Marl site. Because the residual butanes are a valuable raw material for the Scholven refinery, Evonik returns these by pipeline to Gelsenkirchen where it is used as a raw material for the olefin plant. "The project that has now been implemented emphasises the significance of mineral oil processing for the supply chains of the chemical industry. It is a good example for a cross-company cooperation that strengthens competitiveness," says Frederic Baudry, member of the executive board of BP Europa SE and responsible for the petrochemical business of the company.

 

SOURCE ENA News Agency